Tried listening to episode 267 of Back to Work over the last few days, as I had read that Merlin had an interesting perspective on Smile Software's new subscription model for TextExpander. However, he and Dan just bullshit so much about comics and old TV shows, and there is no marker to tell me where to fast-forward to if I just want to hear what I want to hear.
I've listened to a lot of this podcast over the years, and have enjoyed the hosts' meanderings when I've just been walking to work or standing on the train, but I do feel frustrated at times when it takes them so long to get to the 'meat' of the show.
I think this is the big disadvantage of the podcast format. There is no way to scan the content, unless they provide a transcript along with the audio stream. In the hurry-up Internet these days, scanning content is the default mode.